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OBD-II Diagnostic Trouble Code

P0306 — Cylinder 6 Misfire Detected

P0306 means the ECM detected a misfire in cylinder 6, based on crankshaft speed drop during that cylinder's firing event. The misfire rate exceeded an emissions or catalyst-damage threshold. Ignition is the usual cause on gas engines, injector or compression on diesels.

Severity 4/5 Truck-relevant
Stop within 50 mi
Severity
Stop within 50 mi Cylinder 6 Misfire Detected
Code
P0306
Category
Powertrain
Subsystem
Ignition
Truck-relevant
Yes
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What this means for truckers

Cylinder 6 Misfire — same.

Before you replace parts — try this first

P0306 on the Ignition system is most often worn spark plug or failed ignition coil on cylinder 6 (gas engines) — not a dead part. On commercial diesels especially, work these in order before spending money on parts:

  1. Confirm the symptoms. Match what your truck is doing to the Symptoms section below. If the code is set but the symptoms are not there, clear the code and re-test after a drive cycle — it may not return.
  2. Clean and dry the sensor connector. Water, road salt, or oil seeping into a connector is the #1 fake sensor failure. Disconnect, look for green corrosion or moisture, spray with electrical contact cleaner, dry, reseat. Many faults clear here for $0.
  3. Inspect the wiring harness. Trace the wire from the sensor toward the ECM — look for chafing against the engine block, melted insulation near the turbo or exhaust, or pinch points where a clamp has rubbed through.
  4. Test the sensor before swapping it. Most Common Causes (below) list the expected voltage or resistance range — a $20 multimeter saves a $300 sensor swap that does not fix the problem.
  5. Only then, replace the part. Use the OEM or a tier-1 aftermarket. Cheap sensors throw the same code in two weeks.
Symptoms

Rough idle, shaking, hesitation and lower power, with a possible flashing check-engine light on gas trucks and white or gray smoke on diesels.

Common causes
  • CommonWorn spark plug or failed ignition coil on cylinder 6 (gas engines) ($100–$400)
  • CommonFaulty or clogged cylinder 6 injector ($200–$2500)
  • OccasionalLow compression in cylinder 6 ($800–$6000)
  • OccasionalVacuum leak or valvetrain fault on cylinder 6 ($150–$2000)
How to fix
Swap the cylinder 6 coil and plug to another cylinder to see if the misfire follows.
When to use: First step on gas engines.
Run an injector balance or cutout test.
When to use: On diesels, or once ignition is ruled out.
Perform compression and leak-down tests on cylinder 6.
When to use: When fuel and ignition check out.
Replace the faulty component or repair the mechanical fault.
When to use: Once the cause is confirmed.
Affects most

No specific vehicle pattern found in our complaint database. This code can appear on any vehicle that supports OBD-II diagnostics.

Related

Frequently Asked Questions

Can I drive with code P0306?
Drive with caution. P0306 is severity 4 — stop within ~50 miles. Most commercial diesel codes at this severity (turbo, fuel rail, transmission solenoid) can damage adjacent expensive components if left unrepaired. Get to a service location before highway-speed loads.
How much does it cost to fix P0306 on a commercial truck?
Total repair cost ranges $100–$6000 depending on the root cause. The cheapest fix is usually the first one listed below — Worn spark plug or failed ignition coil on cylinder 6 (gas engines) — which is also the most common. On commercial trucks the cost is usually higher than passenger vehicles due to part availability and shop labor rates ($120–185/hour at most truck shops, vs $90–130 at general auto shops). DIY-capable fixes (sensors, hoses, filters) are at the low end; major component replacements (turbo actuator, high-pressure fuel pump, transmission solenoid pack) are at the high end. Always diagnose with a scan tool BEFORE replacing parts — guessing wrong on a $1,500 turbo actuator when the actual issue was a $30 boost hose is a common expensive mistake.
Will P0306 fail a DOT inspection?
P0306 is generally not a direct DOT inspection fail item by itself. Inspectors focus on safety-critical systems (brakes, steering, tires, lights, hours-of-service). However, the check engine light alone can trigger additional inspection scrutiny. Best practice: fix the code and clear it before a planned inspection.
What's the difference between P0306 and related codes?
P0306 is closely related to: P0300 (Random/Multiple Cylinder Misfire Detected), P0301 (Cylinder 1 Misfire Detected), P0302 (Cylinder 2 Misfire Detected), P0303 (Cylinder 3 Misfire Detected). These codes share the same subsystem (ignition) and often appear together. If you see this code, scan for the full code list — fixing the root cause usually clears multiple companion codes at once. If only P0306 is set without the companions, the issue is more isolated.
How do I prevent P0306 from coming back after a repair?
For P0306 (Cylinder 6 Misfire Detected), prevention centers on the ignition system. Use OEM-spec injectors and spark plugs (gas). Address fuel quality issues immediately — bad fuel kills injectors. Cylinder balance test annually for early warning.

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